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IL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia

The bone marrow microenvironment is physiologically hypoxic with areas being as low as 1% O(2), e.g. the stem cell niche. Acute myeloid leukaemia (AML) blasts misuse these bone marrow niches for protection by the local microenvironment, but also might create their own microenvironment. Here we ident...

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Detalles Bibliográficos
Autores principales: Kuett, Alexander, Rieger, Christina, Perathoner, Deborah, Herold, Tobias, Wagner, Michaela, Sironi, Silvia, Sotlar, Karl, Horny, Hans-Peter, Deniffel, Christian, Drolle, Heidrun, Fiegl, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682064/
https://www.ncbi.nlm.nih.gov/pubmed/26674118
http://dx.doi.org/10.1038/srep18411