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IL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia
The bone marrow microenvironment is physiologically hypoxic with areas being as low as 1% O(2), e.g. the stem cell niche. Acute myeloid leukaemia (AML) blasts misuse these bone marrow niches for protection by the local microenvironment, but also might create their own microenvironment. Here we ident...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682064/ https://www.ncbi.nlm.nih.gov/pubmed/26674118 http://dx.doi.org/10.1038/srep18411 |