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The aglycone of ginsenoside Rg3 enables glucagon-like peptide-1 secretion in enteroendocrine cells and alleviates hyperglycemia in type 2 diabetic mice

Ginsenosides can be classified on the basis of the skeleton of their aglycones. Here, we hypothesized that the sugar moieties attached to the dammarane backbone enable binding of the ginsenosides to the sweet taste receptor, eliciting glucagon-like peptide-1 (GLP-1) secretion in the enteroendocrine...

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Detalles Bibliográficos
Autores principales: Kim, Ki-Suk, Jung Yang, Hea, Lee, In-Seung, Kim, Kang-Hoon, Park, Jiyoung, Jeong, Hyeon-Soo, Kim, Yoomi, Seok Ahn, Kwang, Na, Yun-Cheol, Jang, Hyeung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682129/
https://www.ncbi.nlm.nih.gov/pubmed/26675132
http://dx.doi.org/10.1038/srep18325