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PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response

The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). UPR can facilitate the restoration of cellular homeostasis, via the concerted activation of three ER stress sensors, namely IRE1, PERK and ATF6. Global approache...

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Detalles Bibliográficos
Autores principales: Gupta, Ananya, Hossain, Muhammad Mosaraf, Read, Danielle E., Hetz, Claudio, Samali, Afshin, Gupta, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682135/
https://www.ncbi.nlm.nih.gov/pubmed/26674075
http://dx.doi.org/10.1038/srep18304