The effect of androgens on ovarian follicle maturation: Dihydrotestosterone suppress FSH-stimulated granulosa cell proliferation by upregulating PPARγ-dependent PTEN expression.

Intraovarian hyperandrogenism is one of the determining factors of follicular arrest in women with polycystic ovary syndrome (PCOS). Using androgenized rat models, we investigated the effects of androgens on metabolism, as well as on factors involved in follicular arrest and the reduced number of es...

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Detalles Bibliográficos
Autores principales: Chen, Mei-Jou, Chou, Chia-Hung, Chen, Shee-Uan, Yang, Wei-Shiung, Yang, Yu-Shih, Ho, Hong-Nerng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682139/
https://www.ncbi.nlm.nih.gov/pubmed/26674985
http://dx.doi.org/10.1038/srep18319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682139/
https://www.ncbi.nlm.nih.gov/pubmed/26674985
http://dx.doi.org/10.1038/srep18319

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