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Predicting the impact of promoter variability on regulatory outputs

The increased availability of whole genome sequences calls for quantitative models of global gene expression, yet predicting gene expression patterns directly from genome sequence remains a challenge. We examine the contributions of an individual regulator, the ferrous iron-responsive regulatory ele...

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Detalles Bibliográficos
Autores principales: Kreamer, Naomi N., Phillips, Rob, Newman, Dianne K., Boedicker, James Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682146/
https://www.ncbi.nlm.nih.gov/pubmed/26675057
http://dx.doi.org/10.1038/srep18238