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Predicting the impact of promoter variability on regulatory outputs
The increased availability of whole genome sequences calls for quantitative models of global gene expression, yet predicting gene expression patterns directly from genome sequence remains a challenge. We examine the contributions of an individual regulator, the ferrous iron-responsive regulatory ele...
Autores principales: | Kreamer, Naomi N., Phillips, Rob, Newman, Dianne K., Boedicker, James Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682146/ https://www.ncbi.nlm.nih.gov/pubmed/26675057 http://dx.doi.org/10.1038/srep18238 |
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