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Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice

Pluripotent human embryonic stem cells (hESCs) are a potential source of transplantable cells for treating patients with diabetes. To investigate the impact of the host recipient on hESC-derived pancreatic progenitor cell maturation, cells were transplanted into immunodeficient SCID-beige mice or nu...

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Detalles Bibliográficos
Autores principales: Bruin, Jennifer E., Asadi, Ali, Fox, Jessica K., Erener, Suheda, Rezania, Alireza, Kieffer, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682152/
https://www.ncbi.nlm.nih.gov/pubmed/26677767
http://dx.doi.org/10.1016/j.stemcr.2015.10.013