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Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice
Pluripotent human embryonic stem cells (hESCs) are a potential source of transplantable cells for treating patients with diabetes. To investigate the impact of the host recipient on hESC-derived pancreatic progenitor cell maturation, cells were transplanted into immunodeficient SCID-beige mice or nu...
Autores principales: | Bruin, Jennifer E., Asadi, Ali, Fox, Jessica K., Erener, Suheda, Rezania, Alireza, Kieffer, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682152/ https://www.ncbi.nlm.nih.gov/pubmed/26677767 http://dx.doi.org/10.1016/j.stemcr.2015.10.013 |
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