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Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA

High Risk Neuroblastoma (HR-NB) is a pediatric cancer characterized by high malignancy and remarkable cell heterogeneity within the tumour nodules. In a recent study, we demonstrated that in vitro and in vivo over-expression of the non-coding RNA NDM29 (neuroblastoma differentiation marker 29) induc...

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Detalles Bibliográficos
Autores principales: Vella, Serena, Penna, Ilaria, Longo, Luca, Pioggia, Giulia, Garbati, Patrizia, Florio, Tullio, Rossi, Fabio, Pagano, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682181/
https://www.ncbi.nlm.nih.gov/pubmed/26674674
http://dx.doi.org/10.1038/srep18144