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Interleukin-6 trans-signaling increases the expression of carcinoembryonic antigen-related cell adhesion molecules 5 and 6 in colorectal cancer cells

BACKGROUND: Colorectal cancer (CRC) is among the five most frequent causes for cancer-related deaths in Europe. One of the most important tumor-associated antigens for CRC is carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), which is involved in cell adhesion, migration, anoikis,...

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Detalles Bibliográficos
Autores principales: Holmer, Reinhild, Wätzig, Georg H., Tiwari, Sanjay, Rose-John, Stefan, Kalthoff, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682226/
https://www.ncbi.nlm.nih.gov/pubmed/26673628
http://dx.doi.org/10.1186/s12885-015-1950-1