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Epithelial ovarian cancer stem-like cells expressing α-gal epitopes increase the immunogenicity of tumor associated antigens

BACKGROUND: As ovarian cancer stem cells (CSCs) are responsible for tumor initiation, invasion, metastasis, and chemo-resistance, new stratagems that selectively target ovarian CSCs are critically significant. Our previous work have demonstrated that ovarian cancer spheroid cells are tumorigenic and...

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Detalles Bibliográficos
Autores principales: Yao, Xiaofen, Dong, Zhangli, Zhang, Qiuwan, Wang, Qian, Lai, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682262/
https://www.ncbi.nlm.nih.gov/pubmed/26673159
http://dx.doi.org/10.1186/s12885-015-1973-7