Notch-Dependent Pituitary SOX2(+) Stem Cells Exhibit a Timed Functional Extinction in Regulation of the Postnatal Gland

Although SOX2(+) stem cells are present in the postnatal pituitary gland, how they are regulated molecularly and whether they are required for pituitary functions remain unresolved questions. Using a conditional knockout animal model, here we demonstrate that ablation of the canonical Notch signalin...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoyan, Tollkuhn, Jessica, Taylor, Havilah, Rosenfeld, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682291/
https://www.ncbi.nlm.nih.gov/pubmed/26651607
http://dx.doi.org/10.1016/j.stemcr.2015.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682291/
https://www.ncbi.nlm.nih.gov/pubmed/26651607
http://dx.doi.org/10.1016/j.stemcr.2015.11.001

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