Detection of differentially methylated regions from bisulfite-seq data by hidden Markov models incorporating genome-wide methylation level distributions

BACKGROUND: Detection of differential methylation between biological samples is an important task in bisulfite-seq data analysis. Several studies have attempted de novo finding of differentially methylated regions (DMRs) using hidden Markov models (HMMs). However, there is room for improvement in th...

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Detalles Bibliográficos
Autores principales: Saito, Yutaka, Mituyama, Toutai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682380/
https://www.ncbi.nlm.nih.gov/pubmed/26681544
http://dx.doi.org/10.1186/1471-2164-16-S12-S3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682380/
https://www.ncbi.nlm.nih.gov/pubmed/26681544
http://dx.doi.org/10.1186/1471-2164-16-S12-S3

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