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Characterizing informative sequence descriptors and predicting binding affinities of heterodimeric protein complexes

BACKGROUND: Protein-protein interactions (PPIs) are involved in various biological processes, and underlying mechanism of the interactions plays a crucial role in therapeutics and protein engineering. Most machine learning approaches have been developed for predicting the binding affinity of protein...

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Detalles Bibliográficos
Autores principales: Srinivasulu, Yerukala Sathipati, Wang, Jyun-Rong, Hsu, Kai-Ti, Tsai, Ming-Ju, Charoenkwan, Phasit, Huang, Wen-Lin, Huang, Hui-Ling, Ho, Shinn-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682391/
https://www.ncbi.nlm.nih.gov/pubmed/26681483
http://dx.doi.org/10.1186/1471-2105-16-S18-S14