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Characterizing informative sequence descriptors and predicting binding affinities of heterodimeric protein complexes
BACKGROUND: Protein-protein interactions (PPIs) are involved in various biological processes, and underlying mechanism of the interactions plays a crucial role in therapeutics and protein engineering. Most machine learning approaches have been developed for predicting the binding affinity of protein...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682391/ https://www.ncbi.nlm.nih.gov/pubmed/26681483 http://dx.doi.org/10.1186/1471-2105-16-S18-S14 |