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An integrative approach for efficient analysis of whole genome bisulfite sequencing data

BACKGROUND: Whole genome bisulfite sequencing (WGBS) is a high-throughput technique for profiling genome-wide DNA methylation at single nucleotide resolution. However, the applications of WGBS are limited by low accuracy resulting from bisulfite-induced damage on DNA fragments. Although many compute...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Hun, Park, Sung-Joon, Kenta, Nakai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682396/
https://www.ncbi.nlm.nih.gov/pubmed/26680746
http://dx.doi.org/10.1186/1471-2164-16-S12-S14