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An integrative approach for efficient analysis of whole genome bisulfite sequencing data
BACKGROUND: Whole genome bisulfite sequencing (WGBS) is a high-throughput technique for profiling genome-wide DNA methylation at single nucleotide resolution. However, the applications of WGBS are limited by low accuracy resulting from bisulfite-induced damage on DNA fragments. Although many compute...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682396/ https://www.ncbi.nlm.nih.gov/pubmed/26680746 http://dx.doi.org/10.1186/1471-2164-16-S12-S14 |