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Accurate reconstruction of viral quasispecies spectra through improved estimation of strain richness

BACKGROUND: Estimating the number of different species (richness) in a mixed microbial population has been a main focus in metagenomic research. Existing methods of species richness estimation ride on the assumption that the reads in each assembled contig correspond to only one of the microbial geno...

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Detalles Bibliográficos
Autores principales: Jayasundara, Duleepa, Saeed, I, Chang, BC, Tang, Sen-Lin, Halgamuge, Saman K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682401/
https://www.ncbi.nlm.nih.gov/pubmed/26678073
http://dx.doi.org/10.1186/1471-2105-16-S18-S3