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An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer

BACKGROUND: Triple-Negative Breast Cancer (TNBC) is an aggressive disease with a poor prognosis. Clinically, TNBC patients have limited treatment options besides chemotherapy. The goal of this study was to determine the kinase dependency in TNBC cell lines and to predict compounds that could inhibit...

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Detalles Bibliográficos
Autores principales: Ryall, Karen A, Kim, Jihye, Klauck, Peter J, Shin, Jimin, Yoo, Minjae, Ionkina, Anastasia, Pitts, Todd M, Tentler, John J, Diamond, Jennifer R, Eckhardt, S Gail, Heasley, Lynn E, Kang, Jaewoo, Tan, Aik Choon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682411/
https://www.ncbi.nlm.nih.gov/pubmed/26681397
http://dx.doi.org/10.1186/1471-2164-16-S12-S2