Adverse Outcome Pathways can drive non-animal approaches for safety assessment

Adverse Outcome Pathways (AOPs) provide an opportunity to develop new and more accurate safety assessment processes for drugs and other chemicals, and may ultimately play an important role in regulatory decision making. Not only can the development and application of AOPs pave the way for the develo...

Descripción completa

Detalles Bibliográficos
Autores principales: Burden, Natalie, Sewell, Fiona, Andersen, Melvin E, Boobis, Alan, Chipman, J Kevin, Cronin, Mark T D, Hutchinson, Thomas H, Kimber, Ian, Whelan, Maurice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682468/
https://www.ncbi.nlm.nih.gov/pubmed/25943792
http://dx.doi.org/10.1002/jat.3165