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Neutrophil Elastase-Generated Fragment of Vascular Endothelial Growth Factor-A Stimulates Macrophage and Endothelial Progenitor Cell Migration

Elastase released from neutrophils as part of the innate immune system has been implicated in chronic diseases such as emphysema and cardiovascular disease. We have previously shown that neutrophil elastase targets vascular endothelial growth factor-A (VEGF) for partial degradation to generate a fra...

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Detalles Bibliográficos
Autores principales: Kurtagic, Elma, Rich, Celeste B., Buczek-Thomas, Jo Ann, Nugent, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682631/
https://www.ncbi.nlm.nih.gov/pubmed/26672607
http://dx.doi.org/10.1371/journal.pone.0145115