Cargando…

Prediction of Spontaneous Protein Deamidation from Sequence-Derived Secondary Structure and Intrinsic Disorder

Asparagine residues in proteins undergo spontaneous deamidation, a post-translational modification that may act as a molecular clock for the regulation of protein function and turnover. Asparagine deamidation is modulated by protein local sequence, secondary structure and hydrogen bonding. We presen...

Descripción completa

Detalles Bibliográficos
Autores principales: Lorenzo, J. Ramiro, Alonso, Leonardo G., Sánchez, Ignacio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682632/
https://www.ncbi.nlm.nih.gov/pubmed/26674530
http://dx.doi.org/10.1371/journal.pone.0145186