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The Inflammatory Transcription Factors NFκB, STAT1 and STAT3 Drive Age-Associated Transcriptional Changes in the Human Kidney

Human kidney function declines with age, accompanied by stereotyped changes in gene expression and histopathology, but the mechanisms underlying these changes are largely unknown. To identify potential regulators of kidney aging, we compared age-associated transcriptional changes in the human kidney...

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Detalles Bibliográficos
Autores principales: O’Brown, Zach K., Van Nostrand, Eric L., Higgins, John P., Kim, Stuart K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682820/
https://www.ncbi.nlm.nih.gov/pubmed/26678048
http://dx.doi.org/10.1371/journal.pgen.1005734