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The Inflammatory Transcription Factors NFκB, STAT1 and STAT3 Drive Age-Associated Transcriptional Changes in the Human Kidney
Human kidney function declines with age, accompanied by stereotyped changes in gene expression and histopathology, but the mechanisms underlying these changes are largely unknown. To identify potential regulators of kidney aging, we compared age-associated transcriptional changes in the human kidney...
Autores principales: | O’Brown, Zach K., Van Nostrand, Eric L., Higgins, John P., Kim, Stuart K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682820/ https://www.ncbi.nlm.nih.gov/pubmed/26678048 http://dx.doi.org/10.1371/journal.pgen.1005734 |
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