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Increased Protease-Activated Receptor-2 (PAR-2) Expression on CD14(++)CD16(+) Peripheral Blood Monocytes of Patients with Severe Asthma
BACKGROUND: Protease-Activated Receptor-2 (PAR-2), a G protein coupled receptor activated by serine proteases, is widely expressed in humans and is involved in inflammation. PAR-2 activation in the airways plays an important role in the development of allergic airway inflammation. PAR-2 expression i...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682828/ https://www.ncbi.nlm.nih.gov/pubmed/26658828 http://dx.doi.org/10.1371/journal.pone.0144500 |