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Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway

Incursions of new pathogenic viruses into humans from animal reservoirs are occurring with alarming frequency. The molecular underpinnings of immune recognition, host responses, and pathogenesis in this setting are poorly understood. We studied pandemic influenza viruses to determine the mechanism b...

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Detalles Bibliográficos
Autores principales: Hrincius, Eike R., Liedmann, Swantje, Finkelstein, David, Vogel, Peter, Gansebom, Shane, Samarasinghe, Amali E., You, Dahui, Cormier, Stephania A., McCullers, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682876/
https://www.ncbi.nlm.nih.gov/pubmed/26051937
http://dx.doi.org/10.1016/j.celrep.2015.05.012