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A Computational Study of the Factors Influencing the PVC-Triggering Ability of a Cluster of Early Afterdepolarization-Capable Myocytes

Premature ventricular complexes (PVCs), which are abnormal impulse propagations in cardiac tissue, can develop because of various reasons including early afterdepolarizations (EADs). We show how a cluster of EAD-generating cells (EAD clump) can lead to PVCs in a model of cardiac tissue, and also inv...

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Detalles Bibliográficos
Autores principales: Zimik, Soling, Nayak, Alok Ranjan, Pandit, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682961/
https://www.ncbi.nlm.nih.gov/pubmed/26675670
http://dx.doi.org/10.1371/journal.pone.0144979