ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

Epithelial–mesenchymal transition (EMT) is a normal cell differentiation event during development and contributes pathologically to carcinoma and fibrosis progression. EMT often associates with increased transforming growth factor-β (TGF-β) signaling, and TGF-β drives EMT, in part through Smad-media...

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Detalles Bibliográficos
Autores principales: Muthusamy, Baby Periyanayaki, Budi, Erine H., Katsuno, Yoko, Lee, Matthew K., Smith, Susan M., Mirza, Amer M., Akhurst, Rosemary J., Derynck, Rik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682977/
https://www.ncbi.nlm.nih.gov/pubmed/26680585
http://dx.doi.org/10.1371/journal.pbio.1002325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682977/
https://www.ncbi.nlm.nih.gov/pubmed/26680585
http://dx.doi.org/10.1371/journal.pbio.1002325

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