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Xenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled Trial

BACKGROUND: Recently cardiomyocyte progenitor cells (CMPCs) were successfully isolated from fetal and adult human hearts. Direct intramyocardial injection of human CMPCs (hCMPCs) in experimental mouse models of acute myocardial infarction significantly improved cardiac function compared to controls....

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Detalles Bibliográficos
Autores principales: Jansen of Lorkeers, Sanne J., Gho, Johannes M. I. H., Koudstaal, Stefan, van Hout, Gerardus P. J., Zwetsloot, Peter Paul M., van Oorschot, Joep W. M., van Eeuwijk, Esther C. M., Leiner, Tim, Hoefer, Imo E., Goumans, Marie-José, Doevendans, Pieter A., Sluijter, Joost P. G., Chamuleau, Steven A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683045/
https://www.ncbi.nlm.nih.gov/pubmed/26678993
http://dx.doi.org/10.1371/journal.pone.0143953