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Xenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled Trial
BACKGROUND: Recently cardiomyocyte progenitor cells (CMPCs) were successfully isolated from fetal and adult human hearts. Direct intramyocardial injection of human CMPCs (hCMPCs) in experimental mouse models of acute myocardial infarction significantly improved cardiac function compared to controls....
Autores principales: | Jansen of Lorkeers, Sanne J., Gho, Johannes M. I. H., Koudstaal, Stefan, van Hout, Gerardus P. J., Zwetsloot, Peter Paul M., van Oorschot, Joep W. M., van Eeuwijk, Esther C. M., Leiner, Tim, Hoefer, Imo E., Goumans, Marie-José, Doevendans, Pieter A., Sluijter, Joost P. G., Chamuleau, Steven A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683045/ https://www.ncbi.nlm.nih.gov/pubmed/26678993 http://dx.doi.org/10.1371/journal.pone.0143953 |
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