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Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full-length human HP1γ
HP1γ, a non-histone chromatin protein, has elicited significant attention because of its role in gene silencing, elongation, splicing, DNA repair, cell growth, differentiation, and many other cancer-associated processes, including therapy resistance. These characteristics make it an ideal target for...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683166/ https://www.ncbi.nlm.nih.gov/pubmed/26680990 http://dx.doi.org/10.1007/s00894-015-2874-z |