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Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full-length human HP1γ

HP1γ, a non-histone chromatin protein, has elicited significant attention because of its role in gene silencing, elongation, splicing, DNA repair, cell growth, differentiation, and many other cancer-associated processes, including therapy resistance. These characteristics make it an ideal target for...

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Detalles Bibliográficos
Autores principales: Velez, Gabriel, Lin, Marisa, Christensen, Trace, Faubion, William A., Lomberk, Gwen, Urrutia, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683166/
https://www.ncbi.nlm.nih.gov/pubmed/26680990
http://dx.doi.org/10.1007/s00894-015-2874-z

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