N-helix and Cysteines Inter-regulate Human Mitochondrial VDAC-2 Function and Biochemistry

Human voltage-dependent anion channel-2 (hVDAC-2) functions primarily as the crucial anti-apoptotic protein in the outer mitochondrial membrane, and additionally as a gated bidirectional metabolite transporter. The N-terminal helix (NTH), involved in voltage sensing, bears an additional 11-residue e...

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Detalles Bibliográficos
Autores principales: Maurya, Svetlana Rajkumar, Mahalakshmi, Radhakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683249/
https://www.ncbi.nlm.nih.gov/pubmed/26487717
http://dx.doi.org/10.1074/jbc.M115.693978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683249/
https://www.ncbi.nlm.nih.gov/pubmed/26487717
http://dx.doi.org/10.1074/jbc.M115.693978

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