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Quantification of gene-specific methylation of DNMT3B and MTHFR using sequenom EpiTYPER®

Among 272 patients undergoing a screening colonoscopy, DNA methylation of DNMT3B and MTHFR, genes encoding enzymes critical to one-carbon metabolism, was quantified in blood leukocytes using Sequenom EpiTYPER®. DNA methylation was quantified in 66 and 28 CpG sites of DNMT3B and MTHFR respectively, a...

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Detalles Bibliográficos
Autores principales: Ho, Vikki, Ashbury, Janet E., Taylor, Sherryl, Vanner, Stephen, King, Will D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683340/
https://www.ncbi.nlm.nih.gov/pubmed/26759827
http://dx.doi.org/10.1016/j.dib.2015.11.039