Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E

The epithelial to mesenchymal transition (EMT) imparts disease-defining properties to epithelial cells in cancer and organ fibrosis. Prior studies identify EMT control points at the level of transcription and translation, and indicate that activation of translation initiation factor 4E (eIF4E) is in...

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Detalles Bibliográficos
Autores principales: Smith, K. A., Zhou, B., Avdulov, S., Benyumov, A., Peterson, M., Liu, Y., Okon, A., Hergert, P., Braziunas, J., Wagner, C. R., Borok, Z., Bitterman, P. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683370/
https://www.ncbi.nlm.nih.gov/pubmed/26678431
http://dx.doi.org/10.1038/srep18233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683370/
https://www.ncbi.nlm.nih.gov/pubmed/26678431
http://dx.doi.org/10.1038/srep18233

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