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The antimalarial drug primaquine targets Fe–S cluster proteins and yeast respiratory growth

Malaria is a major health burden in tropical and subtropical countries. The antimalarial drug primaquine is extremely useful for killing the transmissible gametocyte forms of Plasmodium falciparum and the hepatic quiescent forms of P. vivax. Yet its mechanism of action is still poorly understood. In...

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Detalles Bibliográficos
Autores principales: Lalève, Anaïs, Vallières, Cindy, Golinelli-Cohen, Marie-Pierre, Bouton, Cécile, Song, Zehua, Pawlik, Grzegorz, Tindall, Sarah M., Avery, Simon V., Clain, Jérôme, Meunier, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683384/
https://www.ncbi.nlm.nih.gov/pubmed/26629948
http://dx.doi.org/10.1016/j.redox.2015.10.008