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Sildenafil reduces signs of oxidative stress in pulmonary arterial hypertension: Evaluation by fatty acid composition, level of hydroxynonenal and heart rate variability

Pulmonary arterial hypertension (PAH) is a rare multifactorial disease with an unfavorable prognosis. Sildenafil therapy can improve functional capacity and pulmonary hemodynamics in PAH patients. Nowadays, it is increasingly recognized that the effects of sildenafil are pleiotropic and may also inv...

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Detalles Bibliográficos
Autores principales: Semen, Khrystyna, Yelisyeyeva, Olha, Jarocka-Karpowicz, Iwona, Kaminskyy, Danylo, Solovey, Lyubomyr, Skrzydlewska, Elzbieta, Yavorskyi, Ostap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683386/
https://www.ncbi.nlm.nih.gov/pubmed/26654977
http://dx.doi.org/10.1016/j.redox.2015.11.009