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“Cation-Stitching Cascade”: exquisite control of terpene cyclization in cyclooctatin biosynthesis

Terpene cyclization is orchestrated by terpene cyclases, which are involved in the biosynthesis of various cyclic natural products, but understanding the origin and mechanism of the selectivity of terpene cyclization is challenging. In this work, we describe an in-depth mechanistic study on cyclooct...

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Detalles Bibliográficos
Autores principales: Sato, Hajime, Teramoto, Kazuya, Masumoto, Yui, Tezuka, Noriyuki, Sakai, Kenta, Ueda, Shota, Totsuka, Yusuke, Shinada, Tetsuro, Nishiyama, Makoto, Wang, Chao, Kuzuyama, Tomohisa, Uchiyama, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683443/
https://www.ncbi.nlm.nih.gov/pubmed/26681256
http://dx.doi.org/10.1038/srep18471