Cargando…
“Cation-Stitching Cascade”: exquisite control of terpene cyclization in cyclooctatin biosynthesis
Terpene cyclization is orchestrated by terpene cyclases, which are involved in the biosynthesis of various cyclic natural products, but understanding the origin and mechanism of the selectivity of terpene cyclization is challenging. In this work, we describe an in-depth mechanistic study on cyclooct...
Autores principales: | Sato, Hajime, Teramoto, Kazuya, Masumoto, Yui, Tezuka, Noriyuki, Sakai, Kenta, Ueda, Shota, Totsuka, Yusuke, Shinada, Tetsuro, Nishiyama, Makoto, Wang, Chao, Kuzuyama, Tomohisa, Uchiyama, Masanobu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683443/ https://www.ncbi.nlm.nih.gov/pubmed/26681256 http://dx.doi.org/10.1038/srep18471 |
Ejemplares similares
-
Emergence of terpene cyclization in Artemisia annua
por: Salmon, Melissa, et al.
Publicado: (2015) -
Structural determinants of reductive terpene cyclization in iridoid biosynthesis
por: Kries, Hajo, et al.
Publicado: (2015) -
Protonation‐Initiated Cyclization by a Class II Terpene Cyclase Assisted by Tunneling
por: Eriksson, Adam, et al.
Publicado: (2017) -
Novel Tryptophan Metabolism by a Potential Gene Cluster That Is Widely Distributed among Actinomycetes
por: Ozaki, Taro, et al.
Publicado: (2013) -
Identification and Characterization of Bacterial Diterpene Cyclases that Synthesize the Cembrane Skeleton
por: Meguro, Ayuko, et al.
Publicado: (2013)