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Identification of potential mitochondrial CLPXP protease interactors and substrates suggests its central role in energy metabolism

Maintenance of mitochondria is achieved by several mechanisms, including the regulation of mitochondrial proteostasis. The matrix protease CLPXP, involved in protein quality control, has been implicated in ageing and disease. However, particularly due to the lack of knowledge of CLPXP’s substrate sp...

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Detalles Bibliográficos
Autores principales: Fischer, Fabian, Langer, Julian D., Osiewacz, Heinz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683621/
https://www.ncbi.nlm.nih.gov/pubmed/26679294
http://dx.doi.org/10.1038/srep18375