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Identification of potential mitochondrial CLPXP protease interactors and substrates suggests its central role in energy metabolism
Maintenance of mitochondria is achieved by several mechanisms, including the regulation of mitochondrial proteostasis. The matrix protease CLPXP, involved in protein quality control, has been implicated in ageing and disease. However, particularly due to the lack of knowledge of CLPXP’s substrate sp...
Autores principales: | Fischer, Fabian, Langer, Julian D., Osiewacz, Heinz D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683621/ https://www.ncbi.nlm.nih.gov/pubmed/26679294 http://dx.doi.org/10.1038/srep18375 |
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