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Metabolomic and Gene Expression Profiles Exhibit Modular Genetic and Dietary Structure Linking Metabolic Syndrome Phenotypes in Drosophila

Genetic and environmental factors influence complex disease in humans, such as metabolic syndrome, and Drosophila melanogaster serves as an excellent model in which to test these factors experimentally. Here we explore the modularity of endophenotypes with an in-depth reanalysis of a previous study...

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Detalles Bibliográficos
Autores principales: Williams, Stephanie, Dew-Budd, Kelly, Davis, Kristen, Anderson, Julie, Bishop, Ruth, Freeman, Kenda, Davis, Dana, Bray, Katherine, Perkins, Lauren, Hubickey, Joana, Reed, Laura K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683653/
https://www.ncbi.nlm.nih.gov/pubmed/26530416
http://dx.doi.org/10.1534/g3.115.023564