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In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon

BACKGROUND: The anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic quinoline anti-malarials (e.g. chloroquine) and semi-synthetic artemisinin derivatives (e.g. artesunate) were developed based on these...

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Detalles Bibliográficos
Autores principales: Lima, Renata B. S., Rocha e Silva, Luiz F., Melo, Marcia R. S., Costa, Jaqueline S., Picanço, Neila S., Lima, Emerson S., Vasconcellos, Marne C., Boleti, Ana Paula A., Santos, Jakeline M. P., Amorim, Rodrigo C. N., Chaves, Francisco C. M., Coutinho, Julia P., Tadei, Wanderli P., Krettli, Antoniana U., Pohlit, Adrian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683771/
https://www.ncbi.nlm.nih.gov/pubmed/26682750
http://dx.doi.org/10.1186/s12936-015-0999-2