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In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon
BACKGROUND: The anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic quinoline anti-malarials (e.g. chloroquine) and semi-synthetic artemisinin derivatives (e.g. artesunate) were developed based on these...
Autores principales: | Lima, Renata B. S., Rocha e Silva, Luiz F., Melo, Marcia R. S., Costa, Jaqueline S., Picanço, Neila S., Lima, Emerson S., Vasconcellos, Marne C., Boleti, Ana Paula A., Santos, Jakeline M. P., Amorim, Rodrigo C. N., Chaves, Francisco C. M., Coutinho, Julia P., Tadei, Wanderli P., Krettli, Antoniana U., Pohlit, Adrian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683771/ https://www.ncbi.nlm.nih.gov/pubmed/26682750 http://dx.doi.org/10.1186/s12936-015-0999-2 |
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