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HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter

BACKGROUND: Intracellular defense proteins, also referred to as restriction factors, are capable of interfering with different steps of the viral life cycle. Among these, we have shown that Tripartite motif 22 (TRIM22) suppresses basal as well as phorbol ester-induced HIV-1 long terminal repeat (LTR...

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Detalles Bibliográficos
Autores principales:	Turrini, Filippo, Marelli, Sara, Kajaste-Rudnitski, Anna, Lusic, Marina, Van Lint, Carine, Das, Atze T., Harwig, Alex, Berkhout, Ben, Vicenzi, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683785/ https://www.ncbi.nlm.nih.gov/pubmed/26683615 http://dx.doi.org/10.1186/s12977-015-0230-0

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