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Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function
BACKGROUND: States of hyperinsulinemia, particularly insulin resistance and type 2 diabetes mellitus, are becoming remarkably common, with roughly half a billion people likely to suffer from the disorder within the next 15 years. Along with this rise has been an associated increased burden of cardio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683786/ https://www.ncbi.nlm.nih.gov/pubmed/26682540 http://dx.doi.org/10.1186/s12933-015-0316-y |