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Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function

BACKGROUND: States of hyperinsulinemia, particularly insulin resistance and type 2 diabetes mellitus, are becoming remarkably common, with roughly half a billion people likely to suffer from the disorder within the next 15 years. Along with this rise has been an associated increased burden of cardio...

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Detalles Bibliográficos
Autores principales: Hodson, Aimee E., Tippetts, Trevor S., Bikman, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683786/
https://www.ncbi.nlm.nih.gov/pubmed/26682540
http://dx.doi.org/10.1186/s12933-015-0316-y