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Substrate stiffness effect and chromosome missegregation in hIPS cells
BACKGROUND: Ensuring genetic stability in pluripotent stem cell (PSC) cultures is essential for the development of successful cell therapies. Although most instances lead to failed experiments and go unreported in the literature, many laboratories have found the emergence of genetic abnormalities in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683860/ https://www.ncbi.nlm.nih.gov/pubmed/26683848 http://dx.doi.org/10.1186/s12952-015-0042-8 |