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Substrate stiffness effect and chromosome missegregation in hIPS cells

BACKGROUND: Ensuring genetic stability in pluripotent stem cell (PSC) cultures is essential for the development of successful cell therapies. Although most instances lead to failed experiments and go unreported in the literature, many laboratories have found the emergence of genetic abnormalities in...

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Detalles Bibliográficos
Autores principales: Acevedo-Acevedo, Suehelay, Crone, Wendy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683860/
https://www.ncbi.nlm.nih.gov/pubmed/26683848
http://dx.doi.org/10.1186/s12952-015-0042-8