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Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson’s disease

BACKGROUND: Deposition of α-synuclein and neuroinflammation are key pathological features of Parkinson’s disease (PD). There is no cure for the disease; however, targeting the pathological features might be available to modulate the disease onset and progression. Hypoestoxide (HE) has been demonstra...

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Detalles Bibliográficos
Autores principales: Kim, Changyoun, Ojo-Amaize, Emmanuel, Spencer, Brian, Rockenstein, Edward, Mante, Michael, Desplats, Paula, Wrasidlo, Wolf, Adame, Anthony, Nchekwube, Emeka, Oyemade, Olusola, Okogun, Joseph, Chan, Michael, Cottam, Howard, Masliah, Eliezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683943/
https://www.ncbi.nlm.nih.gov/pubmed/26683203
http://dx.doi.org/10.1186/s12974-015-0455-9