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Impaired Toll-like receptor 2-mediated Th1 and Th17/22 cytokines secretion in human peripheral blood mononuclear cells from patients with atopic dermatitis

BACKGROUND: Impaired Toll-like receptor 2 (TLR2) function has been associated with the pathogenesis of atopic dermatitis (AD). However, there are only few studies reporting on the TLR2-induced immunological responses of circulating leucocytes of AD patients. We thus investigated the expression and s...

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Detalles Bibliográficos
Autores principales: Yu, Yangyang, Zhang, Yarui, Zhang, Jie, Dou, Xia, Yang, Hong, Shao, Yong, Wang, Kepeng, Yu, Bo, Zhang, Wei, Lau, Hang Yung Alaster
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683963/
https://www.ncbi.nlm.nih.gov/pubmed/26682905
http://dx.doi.org/10.1186/s12967-015-0744-1